(6R*,10R*)-Dimethyl 1,4-dioxaspiro[4.5]decane-6,10-dicarboxylate
نویسندگان
چکیده
منابع مشابه
Dimethyl 2,6,8-trimethyl-1,2-dihydroquinoline-2,4-dicarboxylate
The title compound, C(16)H(19)NO(4), the hydrogenated ring adopts a twisted conformation. In the crystal, inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into centrosymmetric R(2) (2)(10) dimers. These dimers are further connected via inter-molecular N-H⋯O hydrogen bonds, forming infinite double chains along [001].
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In present paper a simple procedure for the synthesis of enaminones without catalyst from 1,3-diketones that reacted with primary or secondary amines in ethanol as solvent, as well as the reaction of enaminones with unsaturated esters such as dimethyl acetylene dicarboxylate are reported.
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in present paper a simple procedure for the synthesis of enaminones without catalyst from 1,3-diketones that reacted with primary or secondary amines in ethanol as solvent, as well as the reaction of enaminones with unsaturated esters such as dimethyl acetylene dicarboxylate are reported.
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Preventing and treating malaria in pregnancy is a global health priority. However little is known regarding the impact of malaria infection on the maternal and fetal disposition of pharmaceuticals and other xenobiotics. Our objective was to characterize expression of key determinants of drug-disposition in maternal and fetal tissues in a validated murine model of experimental placental malaria....
متن کاملExperimental charge density of a potential DHO synthetase inhibitor: dimethyl-trans-2-oxohexahydro-pyrimidine-4,6-dicarboxylate.
The experimental charge density distribution of dimethyl-trans-2-oxohexahydro-pyrimidine-4,6-dicarboxylate 1 has been determined using single-crystal X-ray diffraction data measured at 100 K, in terms of the rigid-pseudoatom formalism. Multipole refinement converged at R(F) = 0.034 for 7283 reflections with I > 3 sigma (I) and sin theta/lambda < or = 1.13 A(-1). Covalent and hydrogen bonding in...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2013
ISSN: 1600-5368
DOI: 10.1107/s160053681300161x